Should we accept our ignorance or disregard it?

(as far as we know) everything is based on this phrase. it's what science is. if we want to advance as intelligent life forms(aka humans) we only have one choice and that is to accept our ignorance, sure that nothing is sure and continue to set out to disprove our proven facts, ask more questions and do what we can to seek the answers, and in this way we get closer to knowing the real answer to the real question.